Zika virus "scarier than the thought" says US

This file photo shows the mosquito Aedes Aegypti photographed on human skin in the laboratory of the International Research Training Center staff and medical (CIDEIM) in Cali, Colombia.
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Zika virus is "scarier" than first thought and its influence on the United States may be greater than expected, public health officials have recognized.
Over a wide range of birth defects has been associated with the virus, said Dr. Anne Schuchat of the US Centers for Disease Control and Prevention.
And the mosquitoes that carry the virus can travel to more US states than previously thought, she said.
The current outbreak of Zika began almost a year ago in Brazil.
This was due to the thousands of birth defects in North and South America.
Media Signature Dr. Anne Schuchat: "All that we are looking at with the virus, it seems a little scary than we originally thought"
"Much of what we have learned, is not encouraging," said Dr. Schuchat at a briefing at the White House on Monday.
"All that we know about this virus seems scarier than we originally thought."
Earlier this year, US President Obama has asked Congress for $ 1.8 billion (£ 1.25 billion) in emergency funding to fight the virus.
At the same time, he used the money totaling $ 589m, the remaining fund from the Ebola virus.
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It was a temporary stopper and are not enough to get the job done, said Dr. Anthony Fauci of the National Institutes of Health.
The US currently needs more money to fight mosquitoes and fund better research of vaccines and treatments, he said.
"When the president asked for $ 1.9 billion, we needed $ 1.9 billion."
He said that was the recent discoveries about how destructive Zeke were in the fetal brain.
Passengers walk sign of Zika virus in the passenger terminal of Incheon International Airport in Incheon, South Korea, on Tuesday, March 22, 2016.Image copyrightAP
Image captionThe the rapid spread of the virus Zika spurred warnings all over the world travel
There were also reports of a rare neurological problems in adults, he said.
CDC announced that Puerto Rico to receive $ 3.9m in emergency funding Zika as the number of cases doubles every week.
In February, the first US case of locally transmitted Zeke reported in Dallas, Texas - spread through sexual contact, rather than a mosquito bite.

Skin Cancer: Drug Couple "to eliminate 20% of tumors"

One-fifth of people with melanoma have no evidence of tumors after treatment in the body with a pair of immunotherapy drugs, research shows.
The first data on survival and nivolumab Ipilimumab use in combination showed 69% of patients in the trial to 142 were still alive after two years.
British doctors, leading the court said that the results were "very encouraging."
Melanoma, the most serious form of skin cancer is the sixth most common cancer in the UK
It kills more than 2,000 people in the UK every year.
These separate studies on melanoma immunotherapy pembrolizumab Merck also showed an increase in survival.
The product also works by reducing the immune system brakes.
The results of the early stage of the trial, published in the Journal of the American Medical Association, showed a third of patients lived for 12 months with no signs of the tumor grow.
Immunotherapy revolution
The immune system is a powerful protection against infection. However, there are a lot of "brake", built to stop it attacking its own tissues.
Cancer - which is a corrupt version of the healthy tissue - can use these brakes to avoid an attack.
Ipilimumab and nivolumab designed to cut off the brakes.
Both have become standard in the treatment of melanoma, but most researchers believe combination therapy would be important.
The study found the survival rate after two years for Ipilimumab alone was 53% and tumor No patient had completely disappeared.
The corresponding figures for the combination therapy was 69% and 22%.
Nevertheless, more than half of the patients had severe life-threatening side effects that stopped treatment.
Dr. James Larkin, who ruled part of the test Marsden Hospital Royal in London, told the website BBC News: "It is very encouraging to see that the level of survival.
"It will be important in terms of development for the benefit of these therapies in the long term, but nevertheless it is a relatively small study so far."
A much larger study involving nearly 1,000 patients have already begun to produce data, but do not work long enough to produce survival rates.
Vicky BrownImage copyrightRoyal Marsden
Vicky Brown, 61 from Cardiff, was diagnosed with malignant melanoma that has spread to her lungs and chest in April of 2013.
She began a combined treatment later in the year.
"He worked for a month. There were lumps I could actually feel, and they disappeared pretty quickly," she told the BBC.
She did have serious side effects, including liver disorder, and inflammatory bowel disease, and a year later the cancer was back.
It is now in its second year of combined immunotherapy, which again seems to reduce swelling.
"My granddaughter is now coming up to four, and now I have a second grandson had not been part of their lives would have been heartbreaking, so I'm very grateful," she added.
Before and Afterimage copyrightRoyal Marsden
captionMelanoma image, before and after therapy
Historically, when treatment fails and the cancer begins to grow again, the fact that the drug becomes useless. But Dr. Larkin said that "we are dealing with something different here."
He added: "This combination of drugs alters the balance of the immune system, the immune system down the line in two years, may no longer recognize the tumor.
"For me it's very encouraging, giving a combination of back, we can re-recognition of the immune system - is a booster."
Both drugs have been developed Bristol-Myers Squibb.
Professor Richard Marais, from Cancer Research UK, said the results were "exciting" and "offer new hope to patients with melanoma and their families."
However, he added: "It is important to remember that there is an increased chance of serious side effects when these drugs are combined.
"We need to determine which patients are likely to benefit from the combination, as well as patients who are likely to experience side effects.
"This will help the doctors to ensure that each patient receives the best treatment that they need."

Cancers of the head and neck of drugs "game changer"

Elderly man with a neck tumourImage copyrightSpl
A new type of cancer drugs, which wakes the patient's own immune system to fight tumors can be a game changer for solutions aggressive types of head and neck cancer, experts say.

The test results out of the US cancer conference suggests that the treatment works better than standard chemotherapy.

Nivolumab significantly improved the chances of survival of patients with these hard-to-treat tumors.

It is now available on the NHS for people with advanced skin cancer.

But experts say that more research is needed before offering it is usually in patients with other cancers.

New Hope

Immunotherapy is considered as one of the most exciting developments in cancer treatments in recent years.

While it may not cure cancer each mounting evidence suggests that you can buy some very sick precious time.

Phase three trial nivolumab, presented at the American Association for Cancer Research, suggests the drug may prolong survival time in months, even when the cancer is advanced and aggressive.

In a study of 240 patients with head and neck cancer were given nivolumab, and another 121 received standard chemotherapy.

A year later, 36% of patients receiving injections nivolumab were still alive, compared with 17% of those on chemo.

The leader of the test British Professor Kevin Harrington of the Institute of Cancer Research and Royal Marsden NHS Foundation Trust, said the results were "a potential game changer" for head and neck cancer, "the introduction of a new drug treatment in our arsenal that is finally better than standard chemotherapy. "

"After she relapsed or spread, head and neck cancer is extremely difficult to treat with surgery and radiation therapy is often not possible," he said.

"So it's very good news for patients, these interim results indicate that we now have a new treatment that works and can significantly prolong life."

About 10 000 patients a year in the UK are diagnosed with head and neck cancer - cancer of the mouth, lips, throat, nose, throat, sinuses and salivary glands.

Dr. Emma King, of Cancer Research UK, said: "These results could have a significant impact on patients with head and neck cancer who no longer respond to treatment.

"They also reinforce the important shift that we have seen in the direction of using immunotherapy to treat cancer.

"Before Nivolumab can be used regularly to treat head and neck cancer in the UK, it must be approved by NICE [National Institute for Health and Clinical Excellence]."

FBR Apple case: Sledovateli vzlamyvatʹ iPhone ó é San Bernardino-bandit

2014 file picture Tashfeen Malik, left, and Rizvan Faruk as they passed through O'Hare International Airport in ChicagoImage copyrightAP
Image captionRizwan Faruk, reconciliation, and his wife Tashfeen Malik, Perils 14 people at the office party in December 2
FBR could unlock iPhone strelâvšego San Bernardino-free use by Apple, ending with the work of the judge, says Ministry of Justice of the United States.

Apple was resistance decree of the court, vypuŝennom last month, trebuûŝuû Office to write new software, to allow a clerk to get access to the phone Rizvan Faruk v.

No clerks on Monday skazal what was available on whether from each other and asked him agencies, to be otozvana.

Rizvan Faruk and his wife Perils of 14 people in San Bernardino in December.

Later they were this person has killed policiej. After slovam amerikanskih clerk, Mr Faruk širokougolʹnuû, Tashfeen Malik, klâlisʹ in such a fidelity to the Islamic nazyvaemym STATE Social media on the day filming.



Last week prokuratura have declared "External side" prodemonstrirovala vozmožnyj way to unlock iPhone without the need to contact Apple for help.

Sudebnoe meeting with Apple, was postponed by the Ministries of Justice of prośbę, this time on how issledoval new sposoby access to the phone.

This time, Apple have declared, what do not know how to get access to, and said, what hopes to what goverment will Share with down-kakie either vulnerabilities in the iPhone, kotorye can prijti the world.


General Manager Media captionApple Tim Cook: "We have Liability to help you satiate your data"
On Monday an application Eileen Decker, top federal Attorney in California, says, sledovateli received aid "tretʹej side" but not utočnil, kto this was.

Sledovateli had "toržestvennoe promise victims Accuracy in San Bernardino," she skazala.

"It is a priority for ÿ goverment to have provided, to pravoohranitelʹnye organy can get važnuû cifrovuû information protection and National Security and Public Safety, either by collaboration with sootvetstvuûŝimi storonami or via sudebnuû system when terpit neudaču partnership," said in an application,

In the answer to this step, Apple Says: "From the beginning, my vozražali against the requirements FBR about what Apple, build a backdoor into the iPhone, ó î þ my, what is this was improper, and has created a precedent by opasnyj. As a result Resignations goverment is not one of them occurred. This case was never required to input ".

Company have declared what will "continue magnifying Safety of our products as Threat and Attack on our data stanovâtsâ all častymi more and more složnymi".

Cracks iPhone: If you worry about?

Court places Image Copyright Getty Images
Image Caption FBI breakthrough means that it helps to avoid the need to deal with Apple's lawyers in court

not a declaration of the US government that it "successfully gain access to data stored in the [San Bernardino gunman] iPhone Farooq and therefore no longer need to" help from Apple's, ends with six weekly legal clash between the technical company and the FBI.

But it leaves the question unresolved dispute on the basis of: The FBI may have forced Apple, to help him unlock the device?

It is unlikely that this will be the last time that law enforcement agencies are trying to force technology companies to help bypass the security measures.

Analysis: Dave Lee, BBC North America Technology reporter, San Francisco

This time last year, Nadella was preparing for a massive launch - Windows 10. For the first time the operating system is free. The goal - to get it on as many devices as possible, because then the fun can begin.

Over 270 million units later, Windows 10, it's time to see what he can do. In 2016 release, the excitement around the AI and AR.

AI - Artificial Intelligence - is only-slightly-jokey reputation as a technology that could potentially lead to the end of humanity as we know it. But this is not "man versus machine", Mr Nadella said, but "the man with the machine."

He said that the bots new applications, as well as demonstrate the assistant Cortana Microsoft's flash - it is integrated into other programs such as Skype. The goal here is to have the ever-present assistant, which grows more intelligent over time.

AR - Augmented Reality - is now ready for developers. First HoloLens Headsets to be sent out, and with it the promise of calculating the events that we had never imagined for education, business and entertainment.

But I must say that the on-screen demo HoloLens are fantastic compared to the fact that the device can actually do today.

How to be run on Windows 10, people asked if Microsoft can drag themselves back into relevance.

Tonight's show AI and AR proves that they were superior. Microsoft is exciting again.